LEO Pharma and MorphoSys enter into strategic alliance to develop therapeutic antibodies in dermatology

LEO Pharma and MorphoSys AG (FSE: MOR; Prime Standard Segment, TecDAX; OTC: MPSYY) today announced that they have entered into a strategic alliance for the discovery and development of therapeutic antibodies for the treatment of skin diseases. The objective of the alliance is to identify novel, antibody-based therapeutics for unmet medical needs that will be valuable additions to both companies’ pipelines.

BALLERUP, Denmark, and MARTINSRIED/MUNICH, Germany 02 November 2016. Collaborating on multiple targets selected by LEO Pharma, the two companies will work together to identify, validate and develop novel therapeutic antibodies. MorphoSys will apply its proprietary Ylanthia technology to generate fully human antibody candidates against the selected targets and will conduct all development activities up to the start of clinical testing. LEO Pharma will be responsible for clinical development and commercialisation of resulting drugs in all indications outside of cancer. In skin cancer indications, MorphoSys will have options to co-develop and, in Europe, co-promote the respective antibody drugs. In addition, MorphoSys will have certain options to develop and commercialise programmes arising from the collaboration in other cancer indications.
 

MorphoSys will receive R&D funding as well as success-based development, regulatory and commercial milestone payments, plus royalties on net sales of drugs commercialised by LEO Pharma. Assuming all development, regulatory and sales objectives are reached, milestone payments would sum up to EUR 111.5 million per antibody programme.
 

“We see exciting potential to develop new treatments for people with skin diseases through our strategic alliance with MorphoSys,” said Gitte Aabo, CEO & President of LEO Pharma. “By joining forces to discover and develop new therapeutic antibodies, we aim to address a high unmet medical need among people with skin diseases. This partnership demonstrates our commitment to expanding our treatment offering and strengthening our position in biologics within dermatology.” 
 

“We are excited to join forces with LEO Pharma in a strategic alliance to develop novel, antibody-based drugs,” said Dr. Simon Moroney, Chief Executive Officer of MorphoSys. “Combining our antibody expertise with LEO Pharma’s deep understanding of dermatology creates an ideal route to products in an area of severe unmet medical need. This alliance is another important step in the execution of our strategy of leveraging our capabilities to build a pipeline of innovative therapeutic antibodies.”
 

About MorphoSys:

MorphoSys developed HuCAL, the most successful antibody library technology in the pharmaceutical industry. By successfully applying this and other patented technologies, MorphoSys has become a leader in the field of therapeutic antibodies, one of the fastest-growing drug classes in human healthcare.

Together with its pharmaceutical partners, MorphoSys has built a therapeutic pipeline of more than 100 human antibody drug candidates for the treatment of cancer, rheumatoid arthritis, and Alzheimer’s disease, to name just a few. With its ongoing commitment to new antibody technology and drug development, MorphoSys is focused on making the healthcare products of tomorrow. MorphoSys is listed on the Frankfurt Stock Exchange under the symbol MOR. For regular updates about MorphoSys, visit http://www.morphosys.com.

HuCAL®, HuCAL GOLD®, HuCAL PLATINUM®, CysDisplay®, RapMAT®, arYla®, Ylanthia®, 100 billion high potentials®, Slonomics®, Lanthio Pharma® and LanthioPep® are registered trademarks of the MorphoSys Group.

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